This question tells the interviewer if you have the hard skills needed and can provide insight into what areas you might need training in. It’s also another way to ensure basic competency. In your answer, include the software the job ad emphasized, any experience with that software you have, and use familiar terminology.
Here’s a sample answer:
“I have a breadth of software experience. For example, at my current employer, I do a lot of ELKI data management and data mining algorithms. I can also create databases in Access and make tables in Excel.”