Can you have a DIV element nested inside a SPAN element?

It is a bad practice to have a DIV element nested inside a SPAN element. You can have a SPAN inside a DIV. The reason being the DIV is a block element and SPAN is an inline element. So, why would you want to have a block element inside an inline element? SPAN is a like sub tag, which applies styles for the specified content in-between the SPAN tag.